🦬 James R. Bosley
DOB: June 9, 1953 · MRN: 14-167-957
Ready
Trial Day
🦬 Be the Buffalo ⚡ Buffalo Charge 🙏 It's in God's Hands
Day
Date
0
Logged
Trial progress — Day ? of 28
Trial Day —
🦬
"Be the Buffalo — Charge into the storm."
Day — of 28 · Keep going, James.
💊 Today's Medications
0 of 17 done 0%
Tap once = ✓ Taken  ·  Tap again = N/A  ·  Tap again = Clear
💧 Water — Goal: 90 oz
0 / 90 oz
0%
Each glass = 8 oz · tap to track
🥩 Protein — Goal: 90g
0 / 90g
0
servings (30g each)
🚶 Miles Walked Today
0.00 miles
0.00
each tap = 0.25 miles
🩺 How do you feel today?
Medications
Verified — Mayo Clinic Pharmacist Review, July 17, 2026
⚠️
Two medications expire 09/24/2026Acetaminophen and OxyCODONE from Mayo Clinic Jacksonville.
⚠️
Missed Daraxonrasib DoseIf not taken within 4 hours of scheduled time, or vomiting occurs — SKIP that dose. Resume tomorrow. Never double-dose.
ℹ️
Skin Care OrderAlways: Acuicyn first → let dry → then Hydrocortisone (face) → then Triamcinolone (trunk).
⭐ Trial Drug
Daraxonrasib (RMC-6236) 150mg
KRAS inhibitor · pancreatic cancer trial drug · IRB 26-006204
Take 2 tablets (300mg) daily with 8oz water · with or without food · do not crush or chew
Lot P126112 · Exp 07/2028 · Rx 221238-0-JAOP · Store below 25°C
🛡️ Skin Toxicity Prevention — Apply in Order
💦
Step 1 · Acuicyn 0.01% SprayDaily
Hypochlorous acid · skin toxicity prevention · FIRST step
Spray on clean dry skin twice daily — morning & evening. Let dry fully before applying creams.
100mL · Pres: Hani M. Babiker MD
🧴
Step 2 · Hydrocortisone (Hytone) 2.5% — FACEDaily
Topical steroid · skin toxicity prophylaxis · FACE ONLY
Apply thin layer to face twice daily — after Acuicyn dries
28g · 1 refill · Pres: Hani M. Babiker MD
🧴
Step 3 · Triamcinolone (Kenalog) 0.1% — TRUNKDaily
Topical steroid · skin toxicity prophylaxis · TRUNK ONLY
Apply thin layer to trunk twice daily — after Acuicyn dries
Rx 6331692-1664 · 80g · Refill 07/09/2027 · Pres: Stephanie Gebhardt ARNP
💊
Doxycycline Hyclate (Vibramycin) 100mgDaily
Antibiotic · prevents skin toxicity · at least 8 weeks
ONE capsule TWICE daily — 8:30 AM and 6:00 PM
Rx 6331683-1664 · 60 caps · Refill 07/09/2027 · Pres: Stephanie Gebhardt ARNP
🦷 Mouth Sore Prevention
🌊
Dexamethasone (Decadron) 0.5mg/5mL Oral RinseDaily
Oral rinse · prevents mouth sores · DO NOT SWALLOW
Swish 10mL for 2 min then SPIT OUT · 3× daily · No food/drink 30–60 min after
1000mL · 1 refill · Pres: Hani M. Babiker MD · ⚠️ NOT the same as Dexamethasone 4mg tablet
🍬
Clotrimazole (Mycelex) 10mg TrocheDaily
Antifungal lozenge · prevents oral fungal infection
Dissolve ONE lozenge in mouth 3× daily · do not chew or swallow whole
Rx 6332899-1664 · 90 lozenges · Refill 07/15/2027 · Pres: Hani M. Babiker MD
🤢 Nausea Protocol
Ondansetron (Zofran) 8mg — PRE-DOSEDaily
Take BEFORE Daraxonrasib every day — scheduled, not just PRN
Take 8mg 30 MINUTES before Daraxonrasib (8:30 AM), then every 8hrs as needed
60 tablets · Pres: Mayo Clinic / Jason Starr MD
1st
Prochlorperazine (Compazine) 10mgPRN
First choice for nausea / vomiting as needed
ONE tablet every 6 hours as needed
Rx 6331680-1664 · 30 tablets · Refill 07/09/2027
2nd
Ondansetron (Zofran) 8mg — As NeededPRN
If Prochlorperazine does not relieve nausea
ONE tablet every 8 hours as needed
90 tablets · Exp Dec 2028 · Pres: Jason Starr MD
3rd
Olanzapine (Zyprexa) 5mgPRN
Severe nausea / vomiting — bedtime
ONE tablet at BEDTIME as needed · may take earlier if needed
Rx 6331681-1664 · 30 tablets · Refill 07/09/2027
🌊 Diarrhea Protocol
💊
Loperamide (Imodium A-D) 2mgPRN
Oncology-specific dosing — different from package instructions
Take 4mg (2 caps) at FIRST sign of diarrhea → then 2mg every 4hrs → until diarrhea-free 12 hrs · MAX 16mg/24hrs
24 caps · 3 refills · Pres: Hani M. Babiker MD
🔄 Cycle / Clinic Medications
💊
Dexamethasone (Decadron) 4mg TabletCycle
Steroid · post-chemo inflammation · TABLET (not the rinse)
TWO tablets (8mg) daily for 12 days · Days 2, 3, 4 AFTER chemo ONLY
Rx 6272845-1664 · 6 tablets · Refill 10/24/2026
🏥
Heparin Flush 100 unit/mL + Saline 0.9%Clinic
Catheter flush · clinic administered every 14 days · NOT self-administered
5mL heparin + 20mL saline via catheter at clinic
Mayo Clinic Jacksonville · 3 refills each
🧴
Lidocaine-Prilocaine (EMLA) 2.5-2.5% CreamPRN
Topical anesthetic · catheter site or skin pain
Apply topically as needed for pain
30g · No refills · Mayo Clinic Jacksonville
😣 Pain Management
💊
Acetaminophen (Tylenol) 500mg⚠️ Exp 09/24/26
Pain relief
ONE tablet every 6 hours as needed for pain
Rx 80618790-300 · 60 tablets · Mayo Clinic Jacksonville
🔴
OxyCODONE (Roxicodone) 5mg IR⚠️ 10 tabs · Exp 09/24/26
Controlled substance · pain management
ONE tablet every 4 hours as needed for pain
Rx 20618789-300 · 10 tablets ONLY · Mayo Clinic Jacksonville
🌿 Supplements
💪
One-A-Day Men's MultivitaminDaily
ONE tablet daily · confirmed by Mayo pharmacist
💨
Chemo Inhaler — AromatherapyPRN
Inhale as needed for nausea (White Ink brand)
👨‍⚕️ Care Team
Hani M. Babiker MD — Lead oncologist, Mayo Clinic Jacksonville
Nahla Ahmed PharmD — Clinical pharmacist, medication review 07/17/2026
Stephanie Gebhardt ARNP — Trial coordinator, Daytona Beach
Jason Starr MD — Additional prescriptions
Revolution Medicines — Trial sponsor · IRB 26-006204
MRN: 14-167-957
Daily Journal
For your medical care team · due by 8:00 PM
1. How did you feel overall today?
😞 Very poor😊 Great
2. Pain level today?
0 — None10 — Severe
3. Energy level?
4. Mood today?
5. New or changed symptoms today?
6. Anything else for your care team?
Past Entries
Most recent first
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Log History
All recorded days — most recent first
🔒
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📈 Water Trend
🔴 Side Effect Summary
Log more days to see patterns.
Contacts & Links
Care team · pharmacy · patient portal
🚨
Emergency — Call 911Chest pain, severe breathing difficulty, loss of consciousness.
🔬 Trial Contacts
💊
Revolution Medicines — Trial Line
Daraxonrasib questions & adverse events
1-844-273-8633 · Mon–Fri 6AM–4PM PST
👩‍⚕️
Stephanie Gebhardt ARNP
Trial coordinator · Daytona Beach · most medications
⚠️ Add number — call Publix (386) 281-6780
👨‍⚕️ Prescribers
👨‍⚕️
Jason Starr MD
Ondansetron · Prochlorperazine
⚠️ Add number — call Publix (386) 281-6780
👨‍⚕️
Hani M. Babiker MD
Lead oncologist · Clotrimazole · Acuicyn · Hydrocortisone
⚠️ Add number — call Publix (386) 281-6780
👨‍👩‍👦 Family
👦
Rick Bosley
Son
⚠️ Add number
🔬 Baseline Labs — July 6, 2026

Mayo Clinic · MRN: 14-167-957

Sodium
141
Potassium
3.9
Creatinine
0.69 ⬇ Low
eGFR
>90
Glucose
95
ALT (Liver)
35
AST (Liver)
29
Bilirubin
0.7
Calcium
9.3
Alk Phos
98
⚠️ When to Call Study Team Immediately
  • Rash spreading rapidly or covering large areas
  • Diarrhea more than 4 times in one day
  • Unable to eat or drink for more than 24 hours
  • Fever above 100.4°F (38°C)
  • New or unusual swelling anywhere
  • Any question about dosing — never skip without calling
  • Acetaminophen or OxyCODONE running low — both expire 09/24/2026
Reminders
Daily medication & journal alerts
⏰ Morning Medication Alarm
8:30 AM
Doxycycline + Zofran before Daraxonrasib
📓 Evening Journal Reminder — 8:00 PM
8:00 PM
Complete your daily journal for the care team
📱 iPhone Setup — Get Notifications
⚠️
One-time setupSave this page to your Home Screen first to enable notifications.
1. Open this page in Safari
2. Tap the Share button (box with arrow ↑)
3. Tap "Add to Home Screen"
4. Tap "Add" — it appears as an app icon
5. Open from Home Screen → Reminders → tap Set Reminder → allow notifications
✅ Daily Reminders
💊 Morning medication
Daraxonrasib with Zofran
💧 Water intake
Track toward 90oz goal
📓 Evening journal
Log for care team by 8PM
✅ Saved